Some new theories are being developed to try to escape the current bottle-necks that have held up the field in unifying different areas of fundamental physics. In short: its time for an overhaul, a change and some fresh ideas.
Our perception of time, for example, doesn't feature in many modern theories in physics e.g. relativity. Symmetries in physics mean that the 'arrow of time' is not distinguishable in the forwards and backwards direction. In a sense, our experiences are entangled in our reading of the universe, that lead us to make theories that have predictive power. Is there a more fundamental level of analysis? Does the universe contain a more uncontaminated form of order that doesn't rely on our involvement in making the boundary conditions of our own theories? These are hard questions that straddle the bridge between hard physics and metaphysics.
But if the pursuit of science has taught us anything, it is that challenging even our most cherished theories can lead to scientific revolutions and in directions that we may not have dreamed possible...